Summary
About the Role
The group activities include identification, validation and development of molecular targets that play a key role in metabolic dysfunction-associated steatohepatitis (MASH, formerly NASH). Advanced projects include investigation of target pharmacology, modulators and biomarkers.
Supervised by an experienced researcher, you will conduct research on hepatocyte biology using in vitro models that may include primary cells and the use of low molecular weight modulators. The studies will involve a variety of techniques and readouts such as molecular biology, microscopy, antibody-based assays. Your role may involve exploratory work as well as supporting targets for which drugs are being developed.
Major accountabilities:
- Designs and executes experiments with input from senior lab members/manager.
- Provides basic data analysis to interpret own experiments ‐ assesses whether experimental hypothesis was appropriately tested and answered.
- Works collaboratively within the lab and project team.
- Participates constructively at lab meetings.
- Steps in to support general lab responsibilities.
- Expected to be an excellent lab citizen.
- Uses understanding of experimental hypothesis and works with manager and colleagues to troubleshoot issues and help design and execute next experiment.
- Experimental results support progression of drug discovery and/or early development projects.
Start date : as soon as possible
Duration : 6 to 7 months
Location: Campus Basel
Minimum Requirements:
- Master degree
- Previous bench work experience in a research laboratory
- Basic molecular biology and cell culture techniques
- Proven capability in experimental design, high quality data delivery, data analysis
- Experience in primary cell culture, flow cytometry, or confocal imaging can be a plus
- Interest in drug discovery and/or hepatology is wished
- Good communication and collaboration skills will be expected
- English: professional working proficiency is required
Accessibility and accommodation:
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to [email protected], and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
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